S23 10 SARM Deus Medical

Type and Article: S-23 (Selective Androgen Receptor Modulator)

S-23 belongs to a class of compounds called Selective Androgen Receptor Modulators (SARMs).²

• Mechanism: SARMs are non-steroidal compounds designed to selectively stimulate androgen (sex hormone) receptors in certain tissues, such as muscle and bone, while minimizing the effects on other tissues like the prostate.³

• Original Development: S-23 was initially developed by a company called GTX, Inc.⁴ and was primarily investigated as a potential male hormonal contraceptive due to its ability to suppress sperm production (spermatogenesis) in animal models, with effects that were shown to be reversible upon cessation of treatment.⁵

 Why Bodybuilders Use S-23

Despite its investigational status, S-23 is used by some in the bodybuilding and athletic communities because it is often purported to:

1. Increase Muscle Mass and Strength: Like other SARMs, users seek S-23 for its strong anabolic effects, hoping to stimulate rapid muscle growth similar to anabolic steroids but with potentially fewer side effects in non-target tissues.

2. Increase Bone Density: Animal studies have suggested S-23 can increase bone mineral density.⁶

3. Reduce Fat Mass: Research in rats showed that S-23 could reduce body fat in a dose-dependent manner.⁷

4. Cutting/Hardening Agent: It is rumored to be one of the most potent SARMs, often used during "cutting" cycles (periods of fat loss) to retain muscle mass and achieve a "harder," more defined physique.

Note: S-23, like all SARMs, is banned by the World Anti-Doping Agency (WADA) and various athletic organizations due to its performance-enhancing effects.⁸

 What Are the Side Effects?

Since S-23 has not undergone full-scale human clinical trials and is not FDA-approved, the full scope of its risks and long-term side effects is unknown. However, preliminary research and warnings from health authorities like the FDA have associated SARMs, including S-23, with serious health risks:⁹

Common/Reported Side Effects:

• Testosterone Suppression: S-23 is known for causing significant and dose-dependent suppression of natural testosterone levels (HPTA axis), which is the intended mechanism for its contraceptive potential.¹⁰ This often requires a Post-Cycle Therapy (PCT) to help restore natural hormone production.

• Testicular Atrophy: As a consequence of hormonal suppression, testicular shrinkage may occur.¹¹

• Infertility: The contraceptive effect involves suppressing spermatogenesis, leading to temporary infertility that may or may not be fully reversible.

• Aggression and Mood Swings (Anabolic/Androgenic effects).

Serious Health Risks (FDA Warnings):

• Liver Injury/Acute Liver Failure: Severe harm to the liver has been associated with SARM use.¹²

• Increased Risk of Heart Attack or Stroke: Cardiovascular complications are a major concern.¹³

• Psychosis and Hallucinations.¹⁴

• Sleep Disturbances.¹⁵

• Sexual Dysfunction.

❓ 4 Frequently Asked Questions (FAQ)

1. Is S-23 legal to buy?

S-23 is generally sold as a "research chemical" and is not approved for human consumption. While the chemical itself may not be scheduled, selling it for human use as a dietary supplement or drug is illegal according to the FDA. The FDA has issued warnings and taken legal action against companies selling products containing SARMs.¹⁶

2. Is S-23 considered a steroid?

No. S-23 is a Selective Androgen Receptor Modulator (SARM).¹⁷ It is a non-steroidal compound.¹⁸ While it mimics some of the anabolic effects of traditional anabolic-androgenic steroids (AAS) by activating androgen receptors, its chemical structure is different and it is designed to be more selective, although this selectivity is not guaranteed in practice.

3. What is the recommended dosage for S-23?

There is no medically established or safe recommended dosage for S-23 because it is an investigational drug, not a prescribed medication or approved supplement. Dosages found on bodybuilding forums are anecdotal and can be extremely unsafe, potentially leading to severe side effects.

4. How long do the suppressive effects of S-23 last?

Because S-23 is highly suppressive of natural testosterone, the effects on the body's hormonal system will persist after the cycle is completed. While studies in animals suggest reversibility, the time it takes for a user's natural hormone levels to fully recover can vary greatly. Many users require a Post-Cycle Therapy (PCT) protocol to attempt to expedite the recovery of their natural testosterone production.

S23 (Mastorin) - Driada Medical EU

The product details S23, an investigational Selective Androgen Receptor Modulator (SARM).¹ S23 is highly potent and was originally studied as a potential male hormonal contraceptive due to its strong suppression of reproductive hormones.²

 Note: S23 is one of the most potent and suppressive SARMs. It is an unapproved investigational drug banned by WADA (World Anti-Doping Agency) due to safety concerns, including liver injury and cardiovascular risks.

Mechanism and Bodybuilding Profile 

S23 is noted for its high binding affinity to the androgen receptor, making it stronger than older SARMs like Andarine.³

• Extreme Anabolic Effects: S23 promotes muscle growth and bone density (anabolic effects).⁴ Animal studies showed a dose-dependent increase in lean body mass (LBM) and suppression of fat mass (FM).⁵

• Contraceptive Potential: S23 was primarily researched as a potential male hormonal contraceptive due to its ability to strongly and reversibly suppress Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH).⁶

• Tissue Selectivity: It is designed to selectively maintain muscle mass while having a relatively less potent effect on androgenic tissues like the prostate.⁷

Usage and Dosage Guidelines (Common Illicit Use) 

• Dosage Range: Due to its potency and strong suppression, doses are typically kept low. Anecdotal illicit doses often range from 10 mg to 30 mg per day. The product is $10 \text{ mg}/\text{tab}$.

• Frequency: Because its half-life is relatively short (around 12 hours), users often split the daily dose into two administrations to maintain stable blood levels.

• Cycle Duration: Cycles are generally kept short (6–8 weeks) due to the strong suppression and potential for severe side effects.

Side Effects and Risks 

S23 is considered a harsh SARM with risks similar to those of traditional potent steroids.

• Severe HPTA Suppression (Major Risk): S23 causes profound and rapid suppression of natural testosterone and fertility (LH and FSH).⁸

  • PCT Required: A very aggressive and extended Post-Cycle Therapy (PCT) using a combination of compounds (like HCG and SERMs) is mandatory after use.

• Hepatotoxicity: The FDA has warned that SARMs, including S23, are associated with risks of liver injury and acute liver failure.⁹

• Cardiovascular Strain: Preliminary research has connected SARMs to an increased risk of heart attack or stroke and negative impacts on the lipid profile (lowering protective HDL cholesterol).¹⁰

• Other Side Effects: Side effects reported for SARMs generally include decreased testicular size, mood swings, sleep disturbances, and acne.¹¹

Frequently Asked Questions (FAQ)

1. What is the primary reason S23 was researched in clinical settings?

S23 was primarily investigated as a potential male hormonal contraceptive due to its highly potent and reversible suppression of sperm production and Luteinizing Hormone (LH).¹²

2. Is Post-Cycle Therapy (PCT) required after using S23?

Yes, PCT is mandatory and must be robust. S23 causes one of the most severe suppressions of natural testosterone and reproductive hormones among all SARMs.

3. What is the typical daily dosage range for S23?

Typical doses often range from 10 mg to 30 mg per day, usually split into two administrations.

4. What are the major known health risks associated with S23 and other SARMs?

Major known health risks include liver injury/failure, increased risk of heart attack or stroke, and severe suppression of the body's natural hormone production.¹³

Manufacturer: Beligas Pharma

Pack: 50 pills x 20 mg

Active Substance: Stenabolic

S-23 is a powerful compound in the Selective Androgen Receptor Modulator (SARM) category, known for its ability to promote muscle growth, fat loss, and enhanced performance. It’s often considered a more targeted and safer alternative to traditional steroids, with fewer side effects. Here’s everything you need to know about S-23:

What is S-23?

S-23 is a SARM that strongly binds to androgen receptors, specifically targeting muscle and bone tissue. It delivers effects similar to steroids but is claimed to significantly reduce common steroid-related side effects, such as liver toxicity or hormonal imbalances.

What Does It Do?

1. Muscle Growth:

   • Increases muscle protein synthesis, leading to rapid and high-quality muscle gains.

   • Boosts strength and endurance significantly.

2. Fat Loss:

   • Helps reduce body fat percentage.

   • Supports fat burning while preserving lean muscle mass.

3. Bone Health:

   • Improves bone density, making bones stronger.

   • May offer protective benefits against bone-related conditions like osteoporosis.

4. Faster Recovery:

   • Speeds up muscle recovery after intense workouts.

   • Reduces fatigue and enhances overall performance.

Role in Bodybuilding

• Muscle Growth: S-23 is popular among athletes and bodybuilders aiming to build muscle mass quickly.

• Fat Loss: It’s effective for improving body composition by reducing fat while maintaining muscle.

• Steroid Alternative: Seen as a safer option for those wanting to avoid the harsh side effects of steroids.

• Performance Boost: Enhances endurance, allowing for longer, more intense training sessions.

How to Use It? Dosage Guidelines

• Standard Dose: The typical dose ranges from 10-20 mg per day.

• Cycle Length: Commonly used in cycles of 8-12 weeks.

• Timing: Can be taken in the morning or before workouts.

• Post Cycle Therapy (PCT): PCT is recommended after the cycle to help restore natural hormone levels.

Side Effects

While S-23 is considered safer than steroids, it’s not without risks:

• Temporary suppression of natural testosterone levels.

• Mild side effects like headaches, fatigue, or stomach discomfort.

• Potential hormonal imbalances with prolonged use.

• Slight increase in liver enzymes (rare).

• Possible changes in libido.

Benefits

1. Promotes rapid and high-quality muscle growth.

2. Supports fat loss while preserving muscle mass.

3. Improves bone density and strength.

4. Enhances workout performance and recovery.

5. Offers fewer side effects compared to traditional steroids.