S4 25 Andarine SARM Deus Medical: A Complete Guide

Type and Article: Andarine (S-4)

Andarine (S-4) is one of the earliest developed Selective Androgen Receptor Modulators (SARMs).¹

• Original Development: It was developed by GTX, Inc.² for treating conditions like muscle wasting (cachexia), osteoporosis, and benign prostatic hyperplasia (BPH).³

• Mechanism: S-4 acts as a partial agonist of the androgen receptor (AR). In certain tissues (like muscle and bone), it activates the receptor, promoting anabolic effects.⁴ In other androgenic tissues (like the prostate), it acts as a partial agonist/competitive antagonist, which theoretically limits the unwanted androgenic side effects seen with traditional anabolic steroids.⁵

• Discontinued Status: Clinical trials for Andarine were discontinued, reportedly due to findings of visual disturbances in human studies.

 Why Bodybuilders Use Andarine (S-4)

Bodybuilders and athletes use Andarine primarily for its reputation as an effective agent for:

• Muscle Mass Maintenance: It is often used during "cutting" cycles where the goal is to lose body fat while strictly preserving existing lean muscle mass.

• Increased Muscle Hardness/Definition: Users report a "hardening" effect on the muscles, giving a more defined and vascular appearance.

• Moderate Anabolic Effects: Compared to other SARMs like LGD-4033 or RAD-140, its anabolic effects are considered more mild, but its partial agonist nature is thought to confer greater tissue selectivity.

Note: Andarine (S-4) is on the World Anti-Doping Agency (WADA) Prohibited List and is banned in competitive sports.

What Are the Side Effects?

The full safety profile and long-term effects of Andarine are unknown, as it never completed clinical trials. The FDA warns that SARMs carry serious risks.⁶

Distinctive and Serious Side Effects of Andarine:

• Visual Disturbances (Most Notorious): This is the key reason its clinical development was halted. Users often report altered color perception (a yellowish tint or xanthopsia) and impaired night vision (difficulty adjusting to low light).⁷ These effects are usually dose-dependent and reversible upon cessation, but they represent a clear toxicity signal.

• Testosterone Suppression: While considered less suppressive than S-23, Andarine will suppress the body's natural testosterone production, often requiring the implementation of a Post-Cycle Therapy (PCT).

Other Potential SARMs Side Effects (Warned by FDA):

• Liver Injury: Cases of liver damage and acute liver failure have been reported with SARM use.⁸

• Cardiovascular Risk: Increased risk of heart attack or stroke.⁹

• Cholesterol Changes: Adverse impact on lipid profiles (decreased HDL, increased LDL).

• Sleep Disturbances, Sexual Dysfunction, and Infertility.¹⁰

 Frequently Asked Questions (FAQs)

1. Is Andarine (S-4) a more potent SARM than Ostarine (MK-2866)?

   Andarine (S-4) is often anecdotally considered more potent for immediate strength and visual muscle "hardness" than Ostarine (MK-2866), particularly in cutting cycles. However, Ostarine is generally considered the "milder" SARM, with fewer reported severe side effects and a better track record in clinical trials, making it often preferred for a first-time SARM user.

2. Is there a safe or established dosage for Andarine?

   No. Because Andarine is an investigational, unapproved drug, there is no medically established, prescribed, or safe dosage for human consumption.11 The dosages discussed on online forums (often $25 \text{ mg}$ to $75 \text{ mg}$) are purely anecdotal and carry a high risk of adverse effects, particularly the visual disturbances.

3. What causes the visual side effects associated with S-4?

   The visual disturbances (yellow tint and night blindness) are believed to be caused by an S-4 metabolite interacting with receptors in the retina of the eye, leading to temporary visual changes.

4. Can Andarine cause liver damage?

   Yes. Like most SARMs, the FDA and various health authorities warn that the use of Andarine and other SARMs is associated with a risk of liver injury and acute liver failure.12 This underscores the significant and known danger of using these unapproved compounds.

Crucial Warning: The use of Andarine (S-4) for human consumption is highly risky. It is an unapproved, banned substance with known adverse side effects, including visual impairment and potential liver and heart issues. Consult a healthcare professional for advice on safe and legal ways to achieve your health and fitness goals.

S4 (Andarine) - Driada Medical EU

The product details S4, commonly known as Andarine. This compound is a Selective Androgen Receptor Modulator (SARM) often used illicitly in bodybuilding for its specific effects on muscle hardening and cutting.

 Note on Consistency: The product packaging information is inconsistent: it lists a concentration of 25 mg/tab in the first line and 10 mg per Tablet in the third line. The summary uses the most frequently stated concentration in the first line (25 mg/tab) but notes the inconsistency.

Mechanism and Key Benefits 

Andarine is an orally active, non-steroidal partial agonist of the Androgen Receptor (AR).¹ It was developed to treat conditions like osteoporosis and muscle wasting.

• Targeted Anabolism: S4 promotes lean muscle growth and is known for its ability to increase muscle hardness and density by binding strongly to ARs in muscle and bone tissue.²

• Fat Loss: It often enhances fat loss, partly by redirecting nutrient partitioning and potentially increasing oxidation, making it highly favored for cutting cycles.

• Preservation: Like Ostarine (MK-2866), it is effective at preserving muscle mass while the user is in a caloric deficit.

• Prostate Selectivity: Research suggests that S4 has a minimal effect on the prostate gland compared to traditional androgens like DHT.³

Usage and Dosage Guidelines (Common Illicit Use) 

• Dosage Range: Common illicit dosages typically range from 25 mg to 50 mg per day.

• Frequency: Some users split the dose into 2–3 administrations daily due to its short half-life (shorter than LGD-4033 or Ostarine).

• Cycle Duration: Generally used for 6–8 weeks.

• Bodybuilding Role: Primarily used for cutting, drying out, and body recomposition.

Side Effects and Risks 

S4 is unique among SARMs for its characteristic side effect, which was a major reason for the discontinuation of its clinical trials.⁴

• Visual Disturbances (Unique Risk): The most common side effect reported anecdotally (and noted in early clinical trials) involves visual disturbances, such as a yellow or green tint to vision and difficulty adjusting vision in low light or darkness (night vision blindness).⁵ These effects are generally reversible upon cessation or dose reduction.

• Testosterone Suppression: Like most SARMs, S4 causes suppression of natural testosterone production in a dose-dependent manner.

  • PCT Required: Post-Cycle Therapy (PCT) with a SERM is usually necessary after an S4 cycle to restore natural hormone function.

• General Health Risks: The FDA has warned that SARMs, including Andarine, are associated with risks such as liver injury and increased risk of heart attack or stroke.⁶

Frequently Asked Questions (FAQ)

1. What is the most unique and common side effect associated with Andarine (S4)?

The most unique and common side effect is visual disturbance, specifically a yellow or green tint to vision and issues with night vision, which prompted the halting of its original clinical development.⁷

2. Why is Andarine popular for cutting cycles?

Andarine is popular for cutting because it helps users preserve lean muscle mass while in a caloric deficit and promotes a visually harder, drier muscle appearance.

3. Does S4 (Andarine) typically require Post-Cycle Therapy (PCT)?

Yes. S4 causes suppression of natural testosterone, making a PCT protocol with SERMs necessary to help the body recover endogenous hormone production.

4. Why might S4 be injected multiple times per day rather than once?

S4 has a relatively short half-life. To maintain stable blood levels and maximize its effect, users often choose to split the daily dose into 2 or 3 separate administrations.

Andarine works by binding to androgen receptors, similar to steroids, but without damaging sex organs; it binds only to muscle and bone receptors. It enhances protein synthesis and metabolism. Andarine increases testosterone levels by 35% without causing estrogen increase or converting to DHT.

Andarine can be used in bulk cycles, cutting cycles, strength gain cycles, or general motivational cycles. Effective usage scenarios include:

For Bulk Cycles:

Those aiming to bulk can use 50mg of Andarine S4 daily alongside 10mg of RAD-140 daily. Caloric intake should be increased during this cycle. It is recommended to cycle for 8-12 weeks.

For Strength Cycles:

To experience power bursts during workouts, it is advised to use 50mg of Andarine S4 daily with 10mg of LGD-4033 daily. A cycle duration of 2-3 weeks is recommended.

For Cutting Cycles:

On paper, Andarine S4 may not appear suitable for cutting, but surprisingly, when combined with Cardarine in a 12-week cycle, it has shown incredible fat-burning effects. You can use 20mg of Cardarine daily along with 40mg of Andarine daily.

For Muscle Gain and Fat Loss Cycle:

It is possible to perform a cycle aimed at both fat loss and muscle gain using 50mg of Andarine , 25mg of Ostarine, and 20mg of Cardarine daily. These three SARMs burn fat and promote muscle gain. It is recommended to cycle this combination for 8-12 weeks.

Andarine (S4) – Beligas Pharma USA (25mg, 50 Tablets)

Product Description:

Andarine (S4) by Beligas Pharma USA is a high-quality Selective Androgen Receptor Modulator (SARM) designed for fat loss, muscle preservation, and enhanced performance. Each pack contains 50 oral tablets dosed at 25mg, making it a reliable option for athletes and bodybuilders who want to achieve a lean, defined physique while maintaining strength and endurance.

Originally researched for treating muscle wasting and osteoporosis, Andarine (S4) is now widely used in bodybuilding as a cutting and recomposition agent due to its ability to burn fat while preserving muscle mass.

Key Features

• Active Ingredient: Andarine (S4)

• Strength: 25mg per tablet

• Pack Size: 50 Tablets

• Form: Oral tablets

• Brand: Beligas Pharma USA

What is Andarine (S4)?

Andarine (S4) is a SARM (Selective Androgen Receptor Modulator) that binds selectively to androgen receptors in muscle and bone tissue. Unlike anabolic steroids, it does not convert to estrogen or DHT, making it a cleaner alternative for physique enhancement.

It is particularly popular in cutting cycles for:

• Fat loss without muscle loss

• Improved muscle hardness & vascularity

• Steady strength retention during calorie deficits

Benefits of Andarine (S4) – Beligas Pharma USA

1. Supports fat loss & body recomposition – effective for cutting phases.

2. Preserves lean muscle mass while dieting.

3. Increases vascularity & muscle hardness for a shredded look.

4. Boosts strength & endurance – improves gym performance.

5. Non-steroidal compound – fewer androgenic and estrogenic side effects.

Dosage and Administration

• Typical Dosage (Men): 25–50mg daily (split into 2 doses)

• Typical Dosage (Women): 10–25mg daily (lower dose recommended)

• Cycle Duration: 6–8 weeks

• Administration: Oral tablets, taken daily

 Note: Higher doses may cause temporary vision side effects (yellow/green tint or night vision difficulty).

Possible Side Effects

While safer than anabolic steroids, possible side effects include:

• Mild testosterone suppression (PCT recommended after cycles)

• Temporary vision disturbances (dose-dependent)

• Headaches or fatigue (rare)

Friendly Suggestion

Since many UGL SARM products are under-dosed or misrepresented, always choose trusted pharmaceutical brands like Beligas Pharma USA. To verify authenticity, check reviews on Reddit, Trustpilot, and bodybuilding forums.

And remember—Andarine (S4) works best when combined with a proper diet, structured training, and PCT support to maintain results post-cycle.